The fresh aloe vera gel pain relief and anti-inflammatory properties as well as its mechanism of action and clinical uses have been used for centuries in the traditional medicine. It contains 12 anthraquinones that are all classified as phenolic compounds or laxatives. The aloe vera gel aloin and emodin chemical components possess analgesic, antibacterial and antiviral properties. The fatty acids of the plant have demonstrated anti-inflammatory actions, while its lupeol component provides antiseptic and analgesic actions. In addition, the salicylic acid of the aloe gel also possesses anti-inflammatory and antibacterial properties. The auxins and gibberellins help in healing the wounds due to its anti-inflammatory action.
The glucomannan polysaccharide and the gibberellin growth hormone interact with the fibroblast receptors. The interaction stimulates and significantly increases the collagen synthesis right after the topical application or right after taking the oral aloe vera.
An increase synthesis of the hyaluronic acid and dermatan sulfate was also reported during the study. The processes efficiently promote an accelerated wound contraction and wound healing.
The slimy tissue inside the aloe leaf is the aloe vera gel where the water is stored and gives the plant the beneficial compounds, such as the vitamins and minerals, amino acids and antioxidants. The reason it works to treat cuts and burns is due to its ability to stimulate and increase collagen production.
The aloe vera gel inhibits inflammation and can be used as a very potent laxative. The process of wound healing is categorized into the inflammatory phase, proliferative phase and the maturation phase into which the biosynthesis of the new collagen by fibroblasts has a key role in the healing process.
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The aloe vera gel contains and provides 20 of the 22 amino acids required by the human body. It also provides 7 out of the 8 essential amino acids. This makes the plant perfect as an ingredient for skin care, aging and in reducing inflammation.
Although the aloe vera gel has been known as a very effective skin moisturizer and a very efficient ingredient for the treatment of thinning hair, the locals are never aware it can work to reduce inflammation and pain.
In fact, several studies confirmed a reduction of the facial wrinkles in women aged over 40 years as well as the ability of the aloe sterols to stimulate the production of the collagen and hyaluronic acid by the human dermal fibroblast. Know that collagen is the major protein that contributes to the tissue strength and restoration of the tissue integrity.
Know that the aloe vera provides the gel for the burns and wounds, but also provides the latex as laxative for the treatment of asthma, diabetes, depression and constipation. Other conditions the aloe vera gel has been reported to efficiently help are
- Burns, frostbite and bruises
- Controls inflammatory pain
- Cleanses the stomach as laxative
- Relieves indigestion and peptic ulcers
- Hair loss and alopecia
- Acne, boils, chronic leg ulcers, skin allergies and dry skin
- Lung disorders, heart disease, stress related disorders and lowers blood glucose in diabetics
- Rheumatoid arthritis
The healing properties of the aloe vera gel are one of the major reasons it has been used as an ingredient in pain relief creams. It has been found very effective in alleviating inflammation and reducing pain levels.
The aloe vera gel can significantly reduce swelling in arthritis without any side effects. In fact, the experimental study conducted in 2014 revealed the extract aloe emodin has the ability to cure arthritis induced in animal models. The study reported significant inhibition of inflammation in arthritic models.
Simply using the aloe vera extracts can help treat osteoarthritis. It has been found capable of replacing non-steroidal anti-inflammatory drugs. The aloe vera gel can be consumed in the form of juice. Drinking it 2 to 3 times a day can potentially reduce inflammation and also relieve pain of rheumatoid arthritis.
For the topical application, a skin patch test is highly recommended. The aloe Vera may cause redness, burning, stinging sensation and in rare cases even dermatitis if it does not suit your skin.
To avoid interactions with drugs, maintain a 3 to 4 hour gap between the medications and aloe vera consumption. Those on medications or suffering from any medical conditions must consult a doctor before starting the consumption of aloe vera on a daily basis.
Intake in longer durations may increase the risk of colorectal cancer. The latex gel, laxative property, may cause an electrolyte imbalance. High oral doses of aloe or aloe latex are dangerous.