Are you tired of using anti aging skin care creams that won’t work? Take your beauty to the next level and start rebuilding from the inside. Adding antioxidants and Coenzyme Q10 dietary supplement to your diet may prevent the acceleration and formation of your wrinkles. The coenzymes work similarly with the vitamins, and is found in every cell of the body. CoQ10 is used by your cells to produce energy required for cell growth and maintenance. Being an antioxidant, it protects the body from the harmful damage caused by free radicals.
CoQ10 diet supplement neutralizes free radicals and at the same time reduces or prevents some of the damage caused by the free radicals. Research has shown that CoQ10 can improve energy production in cells, prevent blood clot formation, and impact your skin positively with its anti aging effects. Production naturally declines as we age.
This coenzyme diet food supplement has been shown to protect against photo aging and premature aging due to sun overexposure. It has the ability to simply stimulate skin cell, which results in skin rejuvenation.
CoQ10 counteracts the process of aging, such as the appearance of a dull, sallow, and wrinkled skin by stimulating collagen production and getting rid of the toxins. Just in case you forgot, collagen protein decreases as you age that leads to the development of wrinkles and leathery skin.
This potent antioxidant is important in maintaining your youthful beauty. It acts against oxidative damage. The damage caused by the sun exposure, pollutants, and stress deliberately result in premature aging.
The decline associated with the ability of the body to convert CoQ10 into its active ubiquinol form is most apparent among those over the age of 40. This diet supplement is recommended for people with heart problems, such as
- A history of heart attacks or coronary heart disease
- High cholesterol
- High blood pressure
- Mitral valve prolapse
This supplement plays a major role in the mitochondrial ATP synthesis, which describes the conversion of raw energy from foods into energy. The process needs the CoQ10 in the inner mitochondrial membrane. The ATP process includes preserving muscle mass to regulating body weight and appetite.
The mitochondrial ATP synthesis maintains a fast metabolism, muscle strength, strong bones, youthful skin and healthy tissue. Researchers believed that a CoQ10 supplementation can slow down the age-related increase in DNA damage. Consuming more CoQ10 may include decreased muscle loss, less signs of skin damage, and protection from bone or joint injuries.
Save your face, save your heart
The vitamin and supplement CoQ10 is mostly found in the mitochondria. It is considered as an important component of the electron transport chain.
Its unique function is to transfer the electrons from the primary substrates to the oxidase system. It also transfers protons to the outside of the mitochondrial membrane.
Without the CoQ10 in the membrane, the regeneration of the tocopherol is very slow. The Coenzyme Q10 (ubiquinone) can be used to rejuvenate cells and stimulate collagen formation, which includes preventing the detrimental effects of photoaging.
The process of aging and photoaging are associated with lower levels of antioxidants in the mitochondria, which leads to the increase in cellular oxidation.
Q10 has been found effective against significantly suppressed collagenase in human dermal fibroblasts and reduced wrinkle depth. One study found that a chronologically aged skin has a lower content of hyaluronic acid and disorganized collagen fibers in the dermal matrix. Using artificially aged human fibroblasts they demonstrated that a 40 mcM of CoQ10 increased the level of hyaluronic acid and also, enhanced by about 20% the proliferation of fibroblasts necessary for the production of collagen.
When applied topically, CoQ10 can even build up in the skin over time. Applying it consistently can provide skin protecting benefits, reduces the depth of wrinkles, and prevents pigmentation.
CoQ10 is the only lipophilic cellular antioxidant synthesized in humans. Its ability to increase the production of basal membrane components and fibroblast proliferation, which includes protecting the cells against the oxidative damage reduces the effects of photoaging with an apparent reduction in wrinkle depth.
Because the CoQ10 can play a role in the remodeling process of the dermal tissue in skin aging, the synthesis of CoQ10 decreases during the aging process, leading to lower plasma and tissue levels in aged people. Wrinkle improvement was reported when a 1% CoQ10 cream was used for 5 months.
Be happy with this. The result of another study showed that CoQ10 can inhibit the production of interleukin-6 and metalloproteinase. The collagen fiber degrading collagenase is a metalloproteinase inhibited by CoQ10, which could lead to the rejuvenation of wrinkled skin. CoQ10 dietary supplement is a very good way to enhance your anti aging skin care.
As an essential electron carrier in cellular respiration during oxidative phosphorylation and ATP synthesis, it acts as a chain breaking antioxidant, clearing ROS and protecting cells from oxidative stress. When topically applied, it has been shown to prevent many of the detrimental effects of photoaging, resulting in a decrease of wrinkle depth.
In the skin, CoQ10 not only preserves antioxidant defense mechanisms that otherwise decrease with intrinsic aging, but it also enhances these defenses to protect against extrinsic aging, especially UV damage. It inhibits UV activation of pro-inflammatory cytokines. Through gene induction, CoQ10 increases the synthesis of collagen and elastin and decreases the expression of metalloproteinases that degrade collagen.
It has been demonstrated that CoQ10 can be topically absorbed, where an application can achieve a 20% penetration into the epidermis and 27% into the dermis. An oral supplementation increases serum and epidermal CoQ10 substantially. Oral supplementation does not increase levels in the dermis or other organs.
By maintaining a proper energy level in the mitochondria, it prevents aging cells from switching to anaerobic energy production. An impairment of the mitochondrial function hinders cellular ATP synthesis, thus reducing the fuel supply for repair mechanisms.
Coenzyme Q10 shows anti aging effects in vivo and in vitro. Phospholipids show restoration effects on collagen synthesis disrupted by UV exposure. CoQ10 can regenerate reduced tocopherol, and without it, the regeneration of tocopherol would be very slow.
When partnered with pycnogenol, which is 50 times more powerful than Vitamin E and 20 times more powerful than Vitamin C, you practically benefit from reduced eye puffiness and redness associated with rosacea and broken capillaries.
The pycnogenol antioxidant contains natural UV protection, fights free radicals, reduces inflammation, smoothens skin, promotes elasticity, stimulates collagen production and reduce fine line.
CoQ10 is necessary for the production of energy in all cells of the body. Don’t you know that skin thickness and its relative changes can be evident as early as age 20 and continues into late adulthood?
In women, the decline of the skin thickness can reach up to 1.13% per year. The thickness of the skin is directly affected by the collagen, elastin, and other substances. Thus, wound healing efficiency can be impaired and decreased with age.
There were claims that it can help in preventing heart failure, cancer, muscular dystrophy, and periodontal disease. Somehow, there were a noted few who claimed they use the anti aging supplement to help reduce the effects of certain medicines on the heart, muscles, and other organs. Several studies suggest that the coenzyme helps the immune system as well as found useful as a secondary treatment for cancer.
What causes the depletion of CoQ10 in your body?
The UV irradiation can cause depletion of the CoQ10 and the antioxidants. The UV rays can cause oxidative damage that sometimes is considered as irreparable.
The CoQ10 can reduce the oxidative stress following the UV irradiation. The cutaneous aging is caused by the decline of the energy metabolism of the skin cells.
This seems to be partially caused by the changes in the mitochondrial respiration and predominantly mediated by the free radicals.
A deficiency is seen as a result of the regular use cholesterol lowering drugs, which deplete the body of CoQ10. A depletion could also occur from polluted air, poor diet, and stress, which cause shortages in important vitamins, such as B complex, which is necessary to produce the CoQ10.
A stiffening of the heart muscle, which causes the body to respond with adrenaline and result in hypertension can be associated with the CoQ10 deficiency. At the Langsjoen clinic, hundreds of patients with mild to moderate hypertension have been normalized within three to six months on CoQ10 alone.
As the blood pressure gradually normalizes, patients are often able to start reducing the amount of medication they take. Obviously, CoQ10 contributed to their quality of life and vigor due to its energizing effect, which made them take less medication.
Medical studies reveal a deficiency of CoQ10 in diabetic patients. They were given 120 mg per day and experienced a reduction of their blood sugar levels by 20 to 30 percent. Research is still needed to clarify the potential role of CoQ10 in diabetes.
Studies also indicate the ability of the dietary supplement to increase the immune system’s firepower against diseases. There is a direct link between aging and the immune system. The immune system effectiveness decreases in the presence of lower CoQ10.
How do you defy aging?
As you age, the levels of CoQ10 in your body also decline, especially in your muscle and skin cells. In some instances, it has been found that a supplementation of the CoQ10 can
- Restore normal tissue levels of an aging or aged skin
It can effectively penetrate into the viable layers of the epidermis and lessen the oxidation caused by a weak photon emission. A reduction of wrinkle depth is seen among clinical studies following a CoQ10 supplementation.
- Suppress the expression of the collagenase in the human dermal fibroblast
This activity usually occurs after UVA irradiation. In some studies, it perfectly demonstrated an efficiency in preventing the detrimental effects of photoaging and its effects in the skin. Several studies have proven the efficacy of the CoQ10 to prevent many of the detrimental effects of photoaging and the resulting general “energizing” effects in the skin.
- Improve the energetic pathways that lead to skin aging
The CoQ10 is one good anti aging intervention strategy. Actually, this food supplement is a high priority in the field of anti aging intervention.
How do you replenish your CoQ10?
Although the CoQ10 declines as you age, you can effectively replenish it by taking the supplement and also, by topical formulation application.
Farage, M. (2010). Textbook of aging skin. Heidelberg: Springer-Verlag.
Vandamme, E. J., & Revuelta, J. L. (2016). Industrial biotechnology of vitamins, biopigments, and antioxidants. Germany: John Wiley & Sons.
Zucker, M., & Challem, J. (2002). Basic health publications user’s guide to CoQ10: Don’t be a dummy. Become an expert of what Coenzyme Q10 can do for your health. North Bergen, NJ: Basic Health Publications.
CoQ10 is one of the dietary supplements I maintained many years now. It is very effective in protecting cells subjected to oxidative stress in patient fibroblast. It is obvious that a reduction of the CoQ10 in a cell impairs the respiratory chain in mitochondria, resulting in an electron jam and excess production of ROS. A small amount of CoQ10 protects a larger amount of tocopherol. In some tissue, such as aged skin, supplemental CoQ10 can restore normal levels, reduces the basal level of oxidation and enhance your anti aging skin care.