A sufficient intake of the glutathione diet supplement as part of your antiaging skincare can actually make you look younger due to its DNA repair action characteristics. In fact, DNA repair in cells has demonstrated dependence on tripeptide glutathione (GSH). This powerful antioxidant helps maintain cellular health and performance. It plays multiple roles in the regulation of cellular homeostasis, including protection against oxidative stress and radiation induced damage in the DNA.
The aging, stress, poor diet, injury, and illnesses contribute to low cellular levels of glutathione in the body. As one ages, the concentration of glutathione in the body drops. This results in the decreased ability of the human body to deactivate free radicals.
The glutathione is actually known as the GSH tri-peptide or small protein molecule formed from the cysteine, glycine, and glutamic acids. It protects the individual cells, tissues of the arteries, brain, heart, immune cells, kidneys, lenses of the eyes, liver, lungs, and skin against oxidant damage.
The antioxidant supplement is highly associated with ageing based on the fact that as humans aged the amount of glutathione in their bodies were found to be highly diminishing. Aging is the result of the deterioration of the physiological functions of the body associated with it.
Several studies have proven the relationship of a decreased intracellular concentrations of glutathione to ageing and survival rates. Many experts consider the glutathione as the body’s first line of defense against oxidative stress and free radicals because it is necessary in protecting the cells from the free radicals as well as in detoxifying the liver.
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Keeping a younger looking skin
You would want to look your best right, so why not stimulate the collagen synthesis? By elevating the collagen production of your body, those fine lines and wrinkles you may have on your face will be greatly reduced.
You should have known that the glutathione levels start to go down at the age of 45 and decline more rapidly at the age of 60. However, having a sufficient level can definitely make you look younger by reducing the photoaging effects on your skin.
The science of Nutrigenomics can be an amazing topic to start some research about keeping a healthy, glowing, wrinkle free skin on any age. Learn about the special foods and substances that can alter the way you physically and mentally age.
Finding a way to stop the subclinical cellular inflammation that prevents wrinkling of the skin can be your simple wrinkle cure. Women who received GSH showed a significant reduction in wrinkles and demonstrated a tendency of increased skin elasticity.
GSH definitely can influence skin properties. The antioxidant has been linked to melanogenesis. Because of the cosmetically important issue of hyperpigmentation, there is a big demand for melanogenesis inhibitors.
Melanogenesis is a process to synthesize melanin, which is primarily responsible for the pigmentation of human skin, eye and hair. Increase in melanin content is correlated with the increase of the tyrosinase activity and the glutathione levels.
Nutrigenomics is the study about how nutrition and dietary supplements can affect your gene expression, which includes the study about certain nutrients that can turn on the genes that block diseases and turn off the genes that causes accelerated ageing.
Scientists published in the Molecular Systems Biology journal that the general wear and tear can be a result of an aging cell detecting serious DNA damage. The internal distress signal triggers the production of the free radical molecules right at the mitochondria itself.
One doctor working in the ICU believed the cellular destruction is associated with the mitochondria resulting in aging. The mitochondria play an important role in controlling the life and death of a cell.
Recently, strategies are being developed for the targeted delivery of antioxidants to mitochondria, where the oxidative stress appears to be critical in its dysfunction that usually leads to a range of diseases.
Metabolism and aging
The fundamental metabolic disturbances as a result of the inadequate tissue oxygenation and the disruption of the body’s ability to control blood sugar levels are a primary cause of the organ dysfunction and failure, which can fast forward to ageing and developing chronic diseases.
You have been probably been told that as you age, you cannot eat like your younger self. It is because as you age, your metabolism tends to slow with age, thus making it easier to pack on the pounds and definitely harder to lose them.
Here is the cue. It has been found that the administration of insulin to rats was followed by a highly significant decrease of the concentration of glutathione in the liver tissue. The decreased concentration was demonstrated in a straight line relationship with time.
The lesson? Sugar reduces your glutathione levels, reduces your metabolism and gives you wrinkles!
Power antioxidant glutathione
The glutathione is a major breakthrough in protecting the body to its cellular level. The combination of a fatty acid attached to the glutathione molecule makes it easy for the glutathione to get easily transported into the cell and into the mitochondria.
Studies have shown they are extremely protective to the fibroblast cells, which are responsible for the production of the collagen and elastin in the skin. Culture studies claimed glutathione regulates the telomerase activity in cells.
Elevating the glutathione levels and other substances that protect the human body against the free radical damage in the mitochondria is the cornerstone of every individual’s quest to look and feel forever young. However, most people should look into the implication of the oral ingestion of the supplemental glutathione.
Oral ingestion of the supplemental glutathione may not be much effective in carrying the glutathione into the cells, because it is rapidly ingested by the gastrointestinal system. Unfortunately, it is impossible to obtain this substance from foods or supplements.
The body needs to manufacture it on site from the nutrients we supply it. You can add more glutathione to your system by supplementing with nutrients and amino acids.
With regular supplementation, they can increase the glutathione content within the cell. Glutathione is the most important molecule you need to stay healthy and prevent ageing, cancer, heart disease, dementia, Alzheimer’s and more.
Consume sulfur rich foods. Try taking the bioactive whey protein, which is a great source of cysteine and the amino acid building blocks for the glutathione synthesis. Immunocal whey protein is listed at the physician’s desk reference. Immunocal is a protein isolate in its purest form. Take the glutathione in its IV form, because you are not going to get much benefit from the pill.
A transdermal delivery is the only possible method that allows the mitochondria to receive the increased levels of this protective tripeptide. When you learn how to adapt this therapeutic intervention as a means of keeping the mitochondria in a youthful state, you will feel forever 30.
It is evident that ageing is characterized by a mitochondrial dysfunction and a disruption of the energy production, which eventually results in a cell death by apoptosis. You can positively affect the way your cells function if you learn how to naturally intervene in the cell death, which is linked with ageing.
To keep your weight at healthy levels and quell cellular inflammation, before it triggers ageing, you need to know exactly what to do to balance your hormones. A quick fix magic bullet approach is not sustainable.
Benefits treatment can include B12 injections, bio-identical hormone replacement therapy, IV Vitamin C therapy, or glutathione injections and IV’s. Hormone balance is your fountain of youth.
You do not decline your hormones because you age. It is the other way around – you age because your hormones decline. Many symptoms of hormonal imbalance can be resolved through good nutrition and smart supplementation.
A power antioxidant like the glutathione supplement can help you look younger and live longer. It beats down the passing of the aging clock, thus making your skin look smoother and younger.
The glutathione has been known as the most powerful among all forms of antioxidants. Taking antioxidants are a real age fix, only if you know how.
The blueberry and the raspberry are said to contain the most number of antioxidants. Resveratrol is an antioxidant found in grapes, red wine, peanuts, chocolate and certain berries that has been credited with a large number of health and aging skin care benefits.
Could other antioxidants work without glutathione? Inside the cell, the glutathione is being synthesized from cysteine, glycine, and glutamate. It simply acts as a substrate for several enzymes, such as the glutathione peroxidase or phospholipids hydroperoxide glutathione peroxidase.
The absence of a glutathione may lead to lipid hydroperoxides accumulation. A glutathione deficiency may increase the hepatic ascorbic acid synthesis. It is believed to enhance the skin’s cellular metabolism and oxygen utilization.
Studies indicate that it can inactivate the tyrosinase and melanin formation, thereby serving as a skin lightening or depigmenting agent. In fact, it is the major antioxidant produced by the cells, that can be held responsible for the essential life processes, such as the DNA repair, cellular exchange of nitrogen, metabolism of iron, and the neutralization of the free radicals and reactive oxygen compounds.
There has been an alarming increase in the unapproved use of the glutathione administered intravenously as skin whitening at very high doses. This practice is not safe and may result in serious consequences for the health of the user.
There is an inadequate safety information on the use of high doses of glutathione administered at 600 mg to 1.2 grams once or even twice weekly.
Boost other antioxidants
The glutathione expands and extends its powerful benefits by boosting the effects of the other antioxidants. Although it is extremely non-absorbable when taken in oral form, you can opt for the IV injections to remedy this disadvantage.
Glutathione plays a role in the protein synthesis, synthesis and repair of DNA, amino acid transport, and the synthesis of hormone like prostaglandins. Glutathione supplies extra electrons to oxidized Vitamin C. The glutathione peroxidases, a group of selenium containing enzymes, provide the antioxidant its wide ranging antiaging effects.
Balch, P. A. (2006). Prescription for nutritional healing. London: Penguin Books Ltd.
Challem, J. (2004). User’s guide to antioxidant supplements: Discover how natural antioxidants can reduce your risk of heart disease, cancer, and Alzheimer’s disease. NJ: Basic Health Publications Inc.
Elsner, P. & Maibach, H. I. (2000). Cosmeceuticals: Drugs vs. cosmetics. New York: Marcel Dekker Inc.
Perricone, N. (2010). Forever young: The science of nutrigenomics for glowing, wrinkle free skin and radiant health at every age. New York: Atria.
Shin, J. W., Nam, K. M., Choi, H. R., Huh, S. Y., Kin, S. W., Youn, S. W., Huh, C. H., & Park, K. C. (2010). Erythrocyte malondialdehyde and glutathione levels in vitiligo patients. Annals of Dermatology, 22(3), 279-283.
Tate, S. A. (2016). Skin bleaching in black atlantic zones: shade shifters. Hampshire: Palgrave Macmillan.
The glutathione plays a critical role in DNA repair and metabolism. It is truly the mother of all antioxidants. Its deficiency causes conditions like ageing and autoimmune disease. Increasing its level through supplementation can help detoxify the body, lose weight, perform better and stay looking younger longer.
The demand for glutathione often exceeds our ability to make and we end up depleted. Without sufficient levels of glutathione often results in DNA damage, developing chronic disease and oxidative stress. It helps prevent oxidative stress by acting as an antioxidant and free radical scavenger. In fact, it is particularly important in defending against oxidative stress in the mitochondria. Poor mitochondrial health is implied in most age related diseases, slow metabolism poor muscle recovery and facilitated ageing, including the appearance of fine lines and wrinkles, which are the signs of aging. For better aging skin care, use the glutathione antioxidant supplement in its IV form.