The CoenzymeQ10 is an important mitochondrial redox component and lipid soluble antioxidant of the human body. The enzyme plays a critical role in the generation of the cellular energy and in boosting the immune system. In addition, it acts as a free radical scavenger and protects the mitochondrial DNA and the energy process from damage.
This nutrient is known as the mitochondria major mover, shaker and protector. A deficiency imperils the heart and it is rather sobering to say that the heart’s natural CoQ10 content at age 80 is less than half of what it is at 20.
We have seen how mutations of the human body’s mitochondrial DNA have caused a loss of energy in cells and eventually contributed to weakness, disease and aging. Over the age of 80, the body will show an accelerated rate of mitochondrial mutation in aging human hearts.
Based on this, preventing oxidative damage in the mitochondrial DNA is therefore critical in warding off any age associated decline with regards to cardiac performance. And it isn’t just an age thing. A CoQ10 deficiency imperils the heart.
The most extreme examples of patients with deficiencies are found among those who got weak hearts and suffering from heart failure. Indeed, most doctors nowadays rescue ailing hearts in both young and old through CoQ10 food supplementation.
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CoQ10 at age 35
After the age of about 35, the human body begins to lose its ability to synthesize CoQ10 from food. Thus, the deficiency may start at this stage. Several studies suggest the supplementation of CoQ10 may sustain the health of the elderly people and even help treat some age-related diseases.
The CoQ10 is the only endogenously synthesized lipid soluble antioxidant found present in all membranes and that has surpassed the amount and efficiency of other antioxidants. The protective effect is extended to lipids proteins and DNA mainly because of its close localization to the oxidative events.
The enzyme along with Vitamin E and Vitamin C plays a key role in the skin protective network. The reduced form of CoQ10 acts as an antioxidant with 10 fold higher levels in the epidermis than in the dermis.
Ageing, poor eating habits, stress and infection affect the ability to provide adequate amounts of CoQ10 in the skin. It decreases with age and under irradiation of the UVA rays.
An oral supplementation of CoQ10 may prove helpful in maintaining skin health. There are several formulations that claimed antioxidant effects, skin repair and regeneration abilities as well as anti-wrinkling and anti-ageing capability.
CoQ10 and cardiovascular disease. The CoQ10 is known to be highly concentrated in the heart muscle cells due to the high energy requirements of this cell type. Some patients with heart failure problems has been linked to the deficiency of the enzyme.
CoQ10 and hypertension. A CoQ10 supplementation may be beneficial in the treatment of hypertension. Short term controlled trials found it resulted in moderate blood pressure decreases in hypertensive individuals. In recent years, common heart drugs creating a CoQ10 deficiency have been uncovered.
CoQ10 and bronchial asthma. Found to be helpful in the treatment of respiratory diseases, especially asthma. Corticosteroid dependent bronchial asthma had been found to have low plasma CoQ10 concentrations that may contribute to developing an antioxidant imbalance and oxidative stress.
CoQ10 and Parkinson disease. The enzyme showed some promise in slowing down the progression of the disease. Several cases have shown an impaired mitochondrial function with a reduced CoQ10 levels in the mitochondria.
Experts say using CoQ10 is like watering a dry plant. It is remarkable and it is powerful. The sicker the patient, the more striking the results. Because the enzyme energizes the viable cells left in the heart, you would experience very dramatic life saving changes.
The heart became more efficient and pumped more blood. Extraordinary clinical improvements were seen in patients expected to die from heart failure, have swelling or edema problems and cardiomyopathy.
CoQ10 is a natural nutrient essential to the life and health of every living cell. Without it, our bodies are unable to fight back against infections and disease. Unfortunately, many of us, especially as we age, lack sufficient CoQ10, putting us at risk of serious illness.
Supplementation has clearly improved the quality of life of older people as well as provide protection against many age related conditions. From a clinical standpoint, doctors believed CoQ10 protects and rejuvenates.
People with heart conditions claimed they have renewed spark and energy. Practically got their life back. But is the long term supplementation of this enzyme safe?
The CoQ10 is a safe antioxidant vitamin used in supplement form for a wide range of diseases. Long term use of even high dosages of over 600 mg daily is still considered very safe.
Some users report the enzyme increases energy levels. You may want to consider taking your supplement in the morning so it cannot interfere with sleep at night. There have been reports from few individuals using the enzyme before bedtime claiming difficulty sleeping. Always take CoQ10 with food to avoid jittery feelings.
Borekova, M., Hojerova, J., Koprda, V., & Bauerova, K. (2008). Nourishing and health benefits of coenzymeQ10 – a review. Czech J. Food Sci., 26(4), pp. 229-241.
Jacobs, B. (1999). Coenzymeq10: All around nutrient for all around health. Tennecula, CA: BL Publications.
Zucker, M. (2002). User’s guide to coenzymeq10. North Bergen, NJ: Basic Health Publications Uder’s Guides.
Every day, the heart muscle expands and contracts about 100,000 times, recycling 2,000 gallons of blood through your body. That takes a lot of energy and yes, a lot of CoQ10. Results include significantly improved quality of life and long term survival from therapeutic supplementation.
Heart failure has been strongly correlated with low blood and tissue levels of CoQ10. The more severe the disease, the greater the CoQ10 deficiency.
Even if you treat patients with a conventional drug, the CoQ10 deficiency still remains. There is no cardiovascular drug that can do for the human body what CoQ10 can do.